U.N. Secretary-General Antonio Guterres warned on Tuesday that the world faces a “generational catastrophe” because of school closures amid the coronavirus pandemic and said that getting students safely back to the classroom must be “a top priority,” Reuters reports.

Guterres said that as of mid-July schools were closed in some 160 countries, affecting more than 1 billion students, while at least 40 million children have missed out on pre-school.

This came on top of more than 250 million children already being out of school before the pandemic and only a quarter of secondary school students in developing countries leaving with basic skills, he said in a video statement.

“Now we face a generational catastrophe that could waste untold human potential, undermine decades of progress, and exacerbate entrenched inequalities,” said Guterres as he launched a U.N. “Save our Future” campaign.

“Once local transmission of COVID-19 is under control, getting students back into schools and learning institutions as safely as possible must be a top priority,” he said. “Consultation with parents, carers, teachers and young people is fundamental.”

The U.N. recommendations for getting global education back on track come as U.S. President Donald Trump pushes for schools to reopen in the face of opposition from some teachers and parents while COVID-19 is surging in many parts of the country.